'Immune Response and Hypersensitivity\r'

'Axia College Material Appendix C repellent Response and Hypersensitivity Puncture affront multimedia system Activity After completing the Puncture Wound Multimedia Activity, complete the table below. List the quadruplet events of the inflammatory response covered in the practise in the order of pop offrence. Rewrite the events in your birth words, using vocabulary terms from Ch. 2 of the text. vascular Events in an Inflammatory Response |Events |Simplified definition of event |Professional description of event | | initiative |Germs from the nail are introduced below the skin. The skin is depressed in some way, in this case by a nail | | | |puncturing the skin. When this occurs, it allows the entry | | | |of pathogens (germs such as bacteria) into the wound. | |2nd |Surrounding cells leak fluid that affects the telephone circuit |An immediate local innate response in the infected tissues | | |vessels. is generated by components of the resistant system which are | | | |pre sent in those tissues.Those components of the immune | | | |system allow in macrophages (a face of white business cell) and | | | |complement proteins (proteins that are involved in the | | | |initial immune response). |third |The fluid affecting the surrounding blood vessels causes | separate immune cells (such as neutrophils), leave the | | |the release of other cells into the tissue. |circulation, attracted by the inflammatory mediators | | | |released by the mast cells and enter the hurt area. | |4th |As the wounded part of the system reacts to the germs, |The neutrophil cells attack the pathogens that have entered | | |certain cells suppress these germs. |the wound and begin to kill them.In the meantime, another | | | | alter immune cell, kn throw as the dendrite cell, carried| | | |parts of the unwarranted pathogen back to the nearby lymphatic | | | |system. | Hypersensitivity Give a brief description and example in your own words for each of the four types of hypersen sitivity presented in Ch. 2. Hypersensitivity matrix Type of Hypersensitivity |Description |Example | |Type I: Allergic/Anaphylactic |Anaphylaxis is an acute|Anaphylaxis is often triggered by substances that are injected or ingested and | | |multi-system severe |thereby prepare access into the blood stream. An explosive reaction involving the skin,| | |type I hypersensitivity|lungs, nose, throat, and gastrointestinal tract can then result. | | |reaction. | |Type II: cytotoxic/Cytolytic |Cytotoxic are caused by|The reaction of the antibody attachment leads to the activation of complement | | |antibodies, which |proteins (again, encountered earlier). The complement proteins destroy the persons | | |attach to a persons |own blood cells.Type II reactions often occur in incompatible blood transfusions. | | |own blood cells or | | | |tissue cells. | |Type III: Immune Complex |An immune complex is |After an antigen-antibody reaction, the immune complexes can be subject to a ny of a | | |formed from the |number of responses, including complement deposition, opsonization, phagocytosis, or| | | full binding of an |processing by proteases. | | |antibody to a oil-soluble | | | |antigen. | |Type IV: Cell-mediated/Delayed|Type IV (cell-mediated)|Cell-mediated immunity is directed primarily at microbes that persist | | |reactions appear 12-72 |in phagocytes and microbes that infect non-phagocytic cells. | | |hours after exposure to| | | |an allergen. | |\r\n'